Journal Basic Info
- Impact Factor: 0.285**
- H-Index: 6
- ISSN: 2638-4558
- DOI: 10.25107/2638-4558
Major Scope
- Palliative Care
- Pulmonary Disease
- Pulmonary Medicine
- Sleep Medicine and Disorders
- Chronic Disease
- Molecular Biology
- Neurological Surgery
- Microbiology
Abstract
Citation: Clin Case Rep Int. 2018;2(1):1050.DOI: 10.25107/2638-4558.1050
A Little Review of LECT2-Associated Renal Amyloidosis (ALECT2): Is not a Rare Disease
Esther Ortega Junco, Sánchez González C, Serrano Pardo R, Lamana Dominguez A, Sanz Sainz M, Saharaui Catala Y, Santos Sánchez B and Sánchez Tomero JA
Nephrology Service, Hospital Universitario de La Princesa, Spain
Pathological Anatomy Service, Hospital Universitario de La Princesa, Spain
Immunology Service, Hospital Universitario de La Princesa, Spain
*Correspondance to: Esther Ortega Junco
PDF Full Text Case Report | Open Access
Abstract:
We present a case of 69-year-old woman, who was referred to our hospital with the diagnosis of Chronic Kidney Disease (CKD) stage IV with unknown etiology. All the complementary tests carried out were normal; with no findings that suggested primary glomerular disease or systemic disease. The urine sediment had no alterations, with minimal proteinuria so at the beginning kidney biopsy was rejected. But after as the kidney function was getting worse and without a clear etiology of the disease; it was decided to carry out the renal biopsy; which showed against all the suspicions amyloid deposits. The pathology we describe is a new form of Amyloidosis, not previously registered in Spain, which differs clinically from the rest of Amyloidosis diseases studied so far. The bland urine sediment, and the slow progress of renal failure, result in an underdiagnosis, because of the kidney biopsy is not usually indicated, which is the only way to reach the diagnosis.
Keywords:
Renal amylodiosis; Leukocyte cell-derived chemotaxin 2-associated amyloidosis; Kidney disease
Cite the Article:
Junco EO, Sánchez González C, Serrano Pardo R, Lamana Dominguez A, Sanz Sainz M, Saharaui CatalaY, et al. A Little Review of LECT2-Associated Renal Amyloidosis (ALECT2): Is not a Rare Disease. Clin Case Rep Int. 2018; 2: 1050.