Journal Basic Info

  • Impact Factor: 0.285**
  • H-Index: 6
  • ISSN: 2638-4558
  • DOI: 10.25107/2638-4558
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Preventive Medicine
  •  Psychiatry
  •  Neonatology
  •  Obstetrics and Gynecology
  •  Sleep Medicine and Disorders
  •  Neurological Surgery
  •  Genetics
  •  Respiratory Medicine

Abstract

Citation: Clin Case Rep Int. 2018;2(1):1054.DOI: 10.25107/2638-4558.1054

Cytophagic Histiocytic Panniculitis Masking as Primary Cutaneous T-Cell Lymphoma: A Spectrum of Disease

Joanna A Kolodney, Naomi Fei, Michael C Lynch, John Nguyen and Michael S Kolodney

Department of Medicine, Division of Hematology/Oncology, West Virginia University, USA
Department of Medicine, West Virginia University, USA
Department of Pathology, West Virginia University, USA
Department of Ophthalmology, West Virginia University, USA
Department of Dermatology, West Virginia University, USA

*Correspondance to: Joanna A Kolodney 

 PDF  Full Text Case Report | Open Access

Abstract:

Primary Cutaneous Gamma-Delta T-Cell Lymphoma (PCGDTCL) comprises of less than 1% of primary Cutaneous T-Cell Lymphomas (CTCL). It is characterized by a highly aggressive clinical course with a median survival of 15 months. PCGDTCL involves the subcutaneous fat and can often mimic both clinically and histologically other more indolent conditions such as Cytophagic Histiocytic Phagocytosis (CHP) and Subcutaneous Panniculitic T-Cell Lymphomas (SPTCL). In addition, diagnosis of PCGDTCL can be challenging due to aberrant expression of surface markers in the neoplastic cells and varied histologic presentation and multiple biopsies are required to make a correct diagnosis. This is a case report that the initial histopathologic findings were most consistent with CHP but with a very aggressive and uncommon clinical course and with extreme subcutaneous ulcerations.

Keywords:

Cite the Article:

Kolodney JA, Fei N, Lynch MC, Nguyen J, Kolodney MS. Cytophagic Histiocytic Panniculitis Masking as Primary Cutaneous T-Cell Lymphoma: A Spectrum of Disease. Clin Case Rep Int. 2018; 2: 1054.

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