Journal Basic Info
- Impact Factor: 0.285**
- H-Index: 6
- ISSN: 2638-4558
- DOI: 10.25107/2638-4558
Major Scope
- Preventive Medicine
- Psychiatry
- Neonatology
- Obstetrics and Gynecology
- Sleep Medicine and Disorders
- Neurological Surgery
- Genetics
- Respiratory Medicine
Abstract
Citation: Clin Case Rep Int. 2018;2(1):1054.DOI: 10.25107/2638-4558.1054
Cytophagic Histiocytic Panniculitis Masking as Primary Cutaneous T-Cell Lymphoma: A Spectrum of Disease
Joanna A Kolodney, Naomi Fei, Michael C Lynch, John Nguyen and Michael S Kolodney
Department of Medicine, Division of Hematology/Oncology, West Virginia University, USA
Department of Medicine, West Virginia University, USA
Department of Pathology, West Virginia University, USA
Department of Ophthalmology, West Virginia University, USA
Department of Dermatology, West Virginia University, USA
*Correspondance to: Joanna A Kolodney
PDF Full Text Case Report | Open Access
Abstract:
Primary Cutaneous Gamma-Delta T-Cell Lymphoma (PCGDTCL) comprises of less than 1% of primary Cutaneous T-Cell Lymphomas (CTCL). It is characterized by a highly aggressive clinical course with a median survival of 15 months. PCGDTCL involves the subcutaneous fat and can often mimic both clinically and histologically other more indolent conditions such as Cytophagic Histiocytic Phagocytosis (CHP) and Subcutaneous Panniculitic T-Cell Lymphomas (SPTCL). In addition, diagnosis of PCGDTCL can be challenging due to aberrant expression of surface markers in the neoplastic cells and varied histologic presentation and multiple biopsies are required to make a correct diagnosis. This is a case report that the initial histopathologic findings were most consistent with CHP but with a very aggressive and uncommon clinical course and with extreme subcutaneous ulcerations.
Keywords:
Cite the Article:
Kolodney JA, Fei N, Lynch MC, Nguyen J, Kolodney MS. Cytophagic Histiocytic Panniculitis Masking as Primary Cutaneous T-Cell Lymphoma: A Spectrum of Disease. Clin Case Rep Int. 2018; 2: 1054.