Clin Case Rep Int | Volume 6, Issue 1 | Research Article | Open Access

Cumulative Rate and Factors Associated with Self- Reported Work Disability among Patients with Systemic Lupus Erythematosus: Data from the Province of Cordoba, Argentina

Bertoli A1,2, López Pérez MJ1, Alba P3, Albiero A4, Albiero E4, Alessio D3, Alvarellos A5, Asbert P4, Astesana P6, Benzaquén N5, Castaños Menescardi MS6, Colazo M5, Encinas L2, Haye Salinas M2, Morales MJ1, Onetti L4, Saurit V5, Savio V7, Werner M4 and Gobbi AC4*

1Catholic University of Córdoba, Argentina
2Ferreyra Hospital, Argentina
3Maternal Neonatal Hospital, Argentina
4National University of Cordoba, Argentina
5Private University Hospital of Córdoba, Argentina
6Strusberg Rheumatological Institute, Argentina
7Italian Hospital, Argentina

*Correspondance to: Carla Andrea Gobbi 

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Background: Systemic Lupus Erythematosus (SLE) can inflict significant morbidity, reflected not only in patients’ overall clinical status but also in their ability to work. Objective: To examine the cumulative rate and factors associated VARIABLES with self-reported work disability in SLE patients in the Province of Córdoba, Argentina. Methods: Two-hundred twenty-five SLE patients were included. The cumulative rate of work disability was estimated using the Kaplan-Meier method. The relationship between socioeconomic and demographic data, self-reported quality of life, clinical features (clinical manifestations, diagnostic criteria, disease activity, damage, co-morbidities) and work disabilities were examined with univariable and multivariable analysis. Results: Fifty-five (24%) patients were work-disabled. The cumulative rate (standard error) of work disability was 5% (0.018) at one year, 25% (0.039) at five years and 54% (0.058) at 10 years. In the multivariable analysis, a lower socio-economic status (OR=1.984; 95% CI 1.154-3.410) and quality of life (OR=0.953, 95% CI 0.914-0.993) were associated with work disability. Conclusion: The cumulative rate of self-reported work disability is high among this sample of SLE patients, reaching 25% at five years. Patients of lower socio-economic status and quality of life are at higher risk of becoming work disabled.


Systemic lupus erythematosus; Work disability; Socio-economic status; Quality of life


Bertoli A, López Pérez MJ, Alba P, Albiero A, Albiero E, Alessio D, et al. Cumulative Rate and Factors Associated with Self-Reported Work Disability among Patients with Systemic Lupus Erythematosus: Data from the Province of Cordoba, Argentina. Clin Case Rep Int. 2022; 6: 1304.

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