Vijayaran M1*, Aggarwal M2, Jasmita D2, Rishi D2, Pradeep K2, Ganesh Kumar V2, Tulika S2, Seema T2 and Manoranjan M2
1Department of Hematology, Hopewell Hospital, India
2Department of Hematology, AIIMS, India
Cytomegalovirus (CMV) infection presenting as severe anemia in infancy is rare. AIHA is a severe hematological manifestation of CMV infection. AIHA is an erythrocyte (RBC) hematologic disorder that is rarely seen in infants and young children. Most cases are associated with viral or bacterial infection, but the immunologic events leading to hemolysis are poorly understood. We report two cases of infants who presented with severe anemia and CMV infection. The first infant had chronic refractory mixed AIHA and the second infant had anemia directly attributable to CMV infection.
Vijayaran M, Aggarwal M, Jasmita D, Rishi D, Pradeep K, Ganesh Kumar V, et al. Cytomegalovirus Infection and Severe Anemia in Infants: Case Report of Two Infants and Review of Literature. Clin Case Rep Int. 2022; 6: 1336.