Clin Case Rep Int | Volume 6, Issue 1 | Case Report | Open Access

Intestinal Type Metaplasia in Renal Pelvis

Rosa Maria Rios-Pelegrina*, Javier L Lopez-Hidalgo, Javier Urrutia and Alexandra J Remon
 

San Cecilio Hospital, Knowledge Avenue S/N, Granada, Spain

*Correspondance to: Rosa Maria Rios-Pelegrina 

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Abstract

Metaplastic changes from urothelium to intestinal type epithelium in the renal pelvis are rare and have the potential of undergoing a malignant transformation to adenocarcinoma. We report a case of intestinal metaplasia in pyelocaliceal and urothelial systems associated to squamous metaplasia without residual urothelium, in a 73-year-old female patient’s right kidney, associated with pyelocaliceal lithiasis, and without malignant transformation. The patient underwent a nephroureterectomy. The metaplastic epithelium’s immunohistochemistry shows positivity to cytokeratin 20, low Ki-67 index, and a lack of expression of p53. In this case, terminal renal illness with the aforementioned metaplastic changes didn’t evolve towards adenocarcinoma, which indicates that intestinal metaplasia doesn’t always imply malignant transformation.

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Citation:

Rios-Pelegrina RM, Lopez-Hidalgo JL, Urrutia J, Remon AJ. Intestinal Type Metaplasia in Renal Pelvis. Clin Case Rep Int. 2022; 6: 1407.

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