Journal Basic Info

  • Impact Factor: 0.285**
  • H-Index: 6
  • ISSN: 2638-4558
  • DOI: 10.25107/2638-4558
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Radiation Oncology
  •  Asthma
  •  Physiotherapy
  •  Cancer Clinic
  •  Hepatitis
  •  Mental Health
  •  Food Science
  •  Breast Neoplasms

Abstract

Citation: Clin Case Rep Int. 2019;3(1):1119.DOI: 10.25107/2638-4558.1119

Use of Trimethoprim-Sulfamethoxazole in Patient with G6PD Deficiency for Treating Pneumocystis Jirovecii Pneumonia

Ya-Wen Lu and Tsung-Chia Chen

Department of Pharmacy, Taichung Hospital, Taiwan Department of Internal Medicine, Taichung Hospital, Taiwan

*Correspondance to: Ya-Wen Lu 

 PDF  Full Text Case Report | Open Access

Abstract:

Case Report: A fixed dose of Trimethoprim-Sulfamethoxazole (TMP/SMZ) is the treatment of choice for Pneumocystis Jirovecii Pneumonia (PJP) recommended by Infectious Diseases Society of America (IDSA). However, TMP/SMZ has been reported to cause hemolysis when administered to patients with deficiency. PJP might be fatal without receiving treatment. Therefore, there is a dilemma on the use of TMP/SMZ in G6PD deficient patients. Herein, we report a G6PD deficient patient with PJP treated successfully with 21 days of TMP/SMZ without any signs and symptoms of hemolysis. Conclusion: It might be safe for the Southeast Asia population with a history of G6PD deficiency to administer TMP/SMZ under expert surveillance.

Keywords:

Glucose-6-phosphate dehydrogenase deficiency; HIV; Pneumocystis pneumonia; Trimethoprim-sulfamethoxazole

Cite the Article:

Lu Y-W, Chen T-C. Use of Trimethoprim-Sulfamethoxazole in Patient with G6PD Deficiency for Treating Pneumocystis Jirovecii Pneumonia. Clin Case Rep Int. 2019;3:1119.

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