Journal Basic Info

  • Impact Factor: 0.285**
  • H-Index: 6
  • ISSN: 2638-4558
  • DOI: 10.25107/2638-4558
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Virology
  •  Pulmonary Disease
  •  Epilepsy and Seizures
  •  Neurological Surgery
  •  Women’s Health Care
  •  Food Science
  •  Cardiovascular Medicine
  •  Hypertension


Citation: Clin Case Rep Int. 2020;4(1):1135.DOI: 10.25107/2638-4558.1135

Gastritis Cystica Profunda: A Case Report and Literature Review

Guofa Yu, Yinguo Du and Zhebing Qiu

Yu G, Du Y, Qiu Z. Gastritis Cystica Profunda: A Case Report and Literature Review. Clin Case Rep Int. 2020; 4: 1135

*Correspondance to: Yinguo Du 

 PDF  Full Text Case Report | Open Access


Gastric Cystica Polyposa (GCP), a rare disease characterized by multiple cystic lesions in mucosa and/or sub mucosal layer, usually occurs in previously operated stomachs. The non-specific clinical symptoms and radiographic appearance make diagnosis difficult without postoperative pathological results. This report aims at providing a comprehensive overview on all GCP cases reported to date. A comprehensive literature search (1972-2014) was conducted for all reported GCP cases, including one case from our group retrospectively. Keywords searched included gastritis cystica profunda, submucosal cysts of the stomach, and heterotopic submucosal gastric glands. A total of 52 cases was found, including 37 (71.2%) men and 15 (28.8%) women (M/F ratio =2.5). The overall mean age was 59.9 (range 39-91) years. Among them, 58.8% (n=30) were located in the body, 25.5% (n=13) in the fundus, 19.6% (n=9) in the antrum, 3.9% (n=2) in the cardia and occasionally one case in the prepyloric lesion and one case in anastomotic site. 52% (n=26) of cases had prior gastric surgery. The main clinical symptoms included abdominal pain (n=14, 36.8%) and gastrointestinal bleeding (including hematemesis and melena, n=7, 18.4%). Among overall 52 cases, only 7.7% (4) were diagnosed before surgery, and the rest were diagnosed during postoperative histopathologic examination. In conclusion, GCP is difficult to be preoperatively correctly diagnosed due to being relatively rare and lack of typical clinical symptoms. The correct diagnosis should depend on histopathological examination. Complete surgical removal of the GCP is widely considered as the best treatment option.


Gastritis cystica profunda; Cystic lesion; Submucosal cysts; Heterotopic submucosal gastric

Cite the Article:

Department of Gastrointestinal Tumor Surgery, Zhejiang University School of Medicine, China.

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