Adult Onset Still’s Disease with Bisitopenia and Very High Ferritine: A Review on Differential Diagnosis and Diagnostic Criteria

Halil İbrahim Erdoğdu and Eray Atalay

Department of Internal Medicine and Hemodialysis, Kafkas University, Turkey

^*Correspondance to: Halil İbrahim Erdoğdu 

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Abstract:

Adult Onset Still Disease (AOSD) is the adult form of systemic juvenile arthritis. It is also one of the important reasons of the unknown fever that is a rare inflammatory disease and causes chronic arthritis. Diagnosis of the disease is made by exclusion of infection, malignancy and rheumatologic diseases. Increased ferritin level is very important to predict the disease. We present a 36-year-old male patient with a history of high fever, sore throat, knee pain, lower extremity rash. As opposed to leukocytosis, leukopenia and thrombocytopenia and a high level of ferritin as high as 15,000 were determined and diagnosed as AOSD according to Yamaguchi criteria. We reviewed the literature and presented it with clinical manifestations and differential diagnoses.

Keywords:

Adult onset still’s disease; High ferritin; Leukopenia; Thrombocytopenia; Negative rheumatoid factor; Negative anti-nuclear antibody

Cite the Article:

Erdoğdu Hİ, Atalay E. Adult Onset Still’s Disease with Bisitopenia and Very High Ferritine: A Review on Differential Diagnosis and Diagnostic Criteria. Clin Case Rep Int. 2020; 4: 1148.