The Risk Factors Associated with the Diabetic Neuropathy Patients from Sensory Functioning and Neurological Symptoms

Li Song, Hong Shi, Li Han and Jirui He

Research Center of the Emergency, The Second Hospital of Lanzhou University, P.R. China
Department of Geriatrics, The Second Hospital of Lanzhou University, P.R. China

^*Correspondance to: Li Song 

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Abstract:

Objective: This clinical study aims to evaluate the risk factors association between the Diabetic Peripheral Neuropathy (DPN) from neuropathic symptoms and nervous sensory signs in patients with DPN. Methods: A total of 81 individuals with DPN participated in this clinical investigation. According to patients’ symptoms, the Neuropathy Symptom Scores (NSS) and their Neuropathy Deficit Scores (NDS) category, four symptom clusters were allocated: No symptoms, mild symptoms, moderate symptoms, and severe symptoms. The four neurological function categories were defined as no signs, mild signs, moderate signs and severe signs. We used an enzyme-linked immunosorbent assay kit to measure the levels of urine 8-Hydroxy-2-Deoxyguanosine (8-OHdG). All statistical tests were performed using the Statistical Package for the Social Sciences, version 25.0 (IBM-SPSS, Chicago, IL, USA). Results: Based on the results of the ordinary logistic regression, it can be concluded that neuropathic sensory function deficits were not related to neuropathic symptoms in patients with DPN; age was associated with neuropathic function deficits in DPN patients; and the level of urine 8-OHdG has no correlation with neuropathic symptoms in patients with DPN. Conclusion: In this clinical study, it can be deduced that the age was related to the neuropathic function deficits in DPN patients and the level of urinary 8-OHdG has no association with the development of neuropathic symptoms in patients with DPN.

Keywords:

Diabetic peripheral neuropathy; Neuropathic symptoms; Neuropathic sensory function; Clinical Study

Cite the Article:

Li Song, Hong Shi, Li Han, Jirui He. The Risk Factors Associated with the Diabetic Neuropathy Patients from Sensory Functioning and Neurological Symptoms. Clin Case Rep Int. 2024; 8: 1694.