A Clinical Case Analysis of Lung Large Cell Neuroendocrine Tumor

Ying Ma and Fei Deng*

The Second Affiliated People's Hospital of China Three Gorges University, China

^*Correspondance to: Fei Deng 

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Abstract:

Introduction: Large Cell Neuroendocrine Carcinoma of the Lung (LCNEC) is a rare and aggressive tumor with a short median survival, mainly due to limited effective treatments. Although Immune Checkpoint Inhibitors (ICIs) have revolutionised the treatment of solid tumors mode, but so far, research on ICI therapy LCNEC is still in its infancy. Case Presentation: We report on a 61-year-old man who was diagnosed with advanced right lung large cell neuroendocrine carcinoma after surgery, through systemic treatment with immune + chemotherapy, radiotherapy for local bone metastases and radiotherapy for postoperative residual lesions, after immune maintenance therapy, the survival time has reached 24 months, during which no tumor recurrence and metastasis was found. Conclusions: Immunotherapy combined with chemotherapy may provide a new treatment modality for patients with advanced large cell neuroendocrine carcinoma of the lung.

Keywords:

Lung large cell carcinoma; Neuroendocrine tumor; Immunotherapy

Cite the Article:

Ma Y, Deng F. A Clinical Case Analysis of Lung Large Cell Neuroendocrine Tumor. Clin Case Rep Int. 2024; 8: 1715..