Uncontrolled Asthma Associated with Allergic Bronchopulmonary Aspergillosis: A Case Report

Quispe-Vicuña C, Coronado-Quispe J, Vargas Ponce KG, Llanos-Tejada FK and Avalos AMO

Department of Cardiology, National University of San Marcos, Peru
Department of Medicine, National University of San Marcos, Peru
Department of Pulmonology, Dos de Mayo National Hospital, Peru

^*Correspondance to: Carlos Quispe-Vicuña 

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Abstract:

Allergic Bronchopulmonary Aspergillosis (ABPA) is an underdiagnosed disease, leading to delayed treatment and major complications such as pulmonary fibrosis, exacerbated bronchiectasis, and severe persistent asthma with loss of lung function. We present the case of a 45-year-old woman, with a history of uncontrolled bronchial asthma, who was admitted to hospital with the initial diagnosis of infected bronchiectasis, which in hospitalization showed persistent bronchospasm associated with eosinophilia, elevated IgE, positive galactomannan antigen (Aspergillus). In TACAR there was evidence of bronchiectasis of bilateral central location. The patient was treated with corticosteroids and antifungal agents, showing clinical improvement in his outpatient controls. Serological detection tests for Aspergillus fumigatus, together with TACAR, are important in asthmatic patients, particularly in uncontrolled patients, since a timely diagnosis and treatment will improve the prognosis and quality of life of these patients.

Keywords:

Asthma; Allergic bronchopulmonary aspergillosis; Aspergillosis

Cite the Article:

Quispe-Vicuña C, Coronado-Quispe J, Vargas Ponce KG, Llanos-Tejada FK, Avalos AMO. Uncontrolled Asthma Associated with Allergic Bronchopulmonary Aspergillosis: A Case Report. Clin Case Rep Int. 2022; 6: 1412.