Probiotics-Induced Acute Urticaria in a Pediatric Patient: A Case Report

Md. Hasan J, Md. Rahman M and Bachar SC

Department of Pharmacy, Square Hospitals Ltd., Bangladesh
Department of Pediatrics, Square Hospitals Ltd., Dhaka, Bangladesh
Department of Pharmacy, University of Dhaka, Bangladesh

^*Correspondance to: Md. Jahidul Hasan 

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Abstract:

Background: Acute urticaria is a suddenly developed pruritus, pale red bump on the skin as a result of an allergic reaction which is triggered by a stimulus, such as a drug and can be disappeared within 48 hours. Probiotics are host-friendly live microorganisms those can restrengthen the intestinal microbial flora and are widely used mostly in the management of acute diarrhea. Probiotics-induced adverse drug reactions like, urticaria is an unusual incidence and here we found an event of probiotics-induced acute urticaria.
Case Description: An 18-month-old pediatric patient was suffering from diarrhea for last 2 days and took the consultation of a doctor. He was prescribed with probiotics (a combination of Lactobacillus acidophilus-2 billion, Lactobacillus bulgaricus-1 billion and Bifidobacterium bifidum-1 billion) at a dose: one capsule per day orally. On the day one, the patient was experienced with probiotics-induced acute urticaria just after 3 and half hour of ingestion, and most of the symptoms of urticaria were resolved within 4 hr to 5 hrs without any anti-allergy medication. Same incidence happened in the second day. As per the doctor’s advice, probiotics were discontinued and he was not experienced with any allergic reaction, after that.
Conclusion: Any drug may be treated as an allergen by a living human body and consequently, may develop allergic reactions such as, urticaria. Although, probiotics are considered as safe drugs, but in our case, we found a usual probiotics-induced acute urticaria case in a pediatric patient.

Keywords:

Acute Urticaria; Probiotics; Adverse Drug Reactiona

Cite the Article:

Md. Hasan J, Md. Rahman M, Bachar SC. Probiotics-Induced Acute Urticaria in a Pediatric Patient: A Case Report. Clin Case Rep Int. 2019; 3: 1090.