Schistosomiasis Mansoni Cerebral Pseudotumor

Mukisa R, Musubire AK, Alupo P, Kaddumukasa M, Kaddumukasa M, Muhumuza M and Matovu S

Department of Medicine, Makerere University, Uganda 2 Department of Surgery, Makerere University, Uganda

^*Correspondance to: Robert Mukisa 

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Abstract:

We describe a case report of a potentially treatable condition of Schistosomiasis mansoni cerebral pseudotumor in Uganda, an ectopic form of the disease that is mainly associated with Schistosoma japonicum. It is presumed to be extremely rare, neglected and underestimated despite the high prevalence of schistosomiasis mansoni in many developing countries. This is a 25 year-old man who presented with a history of recurrent seizures despite anticonvulsants and headaches unresponsive to non-steroidal anti-inflammatory drugs. Brain Magnetic resonance imaging revealed a T1 Gadolinium enhancing lesion with surrounding edema and mild mass effect in the right occipital lobe. He underwent brain surgery for possible meningioma but biopsy demonstrated intraparenchymal granulomas surrounding Schistosoma mansoni eggs on histology. Praziquantel was started (60 mg/kg of body weight, in a single dose) and Prednisone (80 mg/day) for seven days to treat the cerebral edema. The patient’s symptoms resolved following medical treatment and the follow-up brain MRI was normal.

Keywords:

Schistosomiasis; Brain; Pseudo tumor

Cite the Article:

Mukisa R, Musubire AK, Alupo P, Kaddumukasa M, Kaddumukasa M, Muhumuza M, et al. Schistosomiasis Mansoni Cerebral Pseudotumor. Clin Case Rep Int. 2019; 3: 1099.