Journal Basic Info

  • Impact Factor: 0.285**
  • H-Index: 6
  • ISSN: 2638-4558
  • DOI: 10.25107/2638-4558
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Neonatology
  •  Physiotherapy
  •  Preventive Medicine
  •  Gastroenterology
  •  Radiology
  •  Infectious Disease
  •  Surgical
  •  ENT


Citation: Clin Case Rep Int. 2023;6(1):1601.DOI: 10.25107/2638-4558.1601

The Future of Breast Cancer in Pakistan in the Age of New Gene Mutation

Ahmed S, Ansari AI and Ansari Z

Department of Internal Medicine, Dow University of Health Sciences, Pakistan

*Correspondance to: Zobia Ansari 

 PDF  Full Text Short Communication | Open Access


Breast cancer is influenced by factors like advanced age, family history, early menstruation, lactation difficulties, and late menopause. Hereditary breast cancer often involves mutations in BRCA1 and BRCA2 genes. Recently, researchers identified a new gene mutation, ATRIP, associated with an increased risk of breast cancer, particularly in Pakistani women, leading to early-onset breast cancer. PARP inhibitors have shown promise in treating breast tumors with ATRIP mutations. However, Pakistan faces challenges in handling the escalating breast cancer cases due to limited resources and modifications in the future. Immediate action is crucial to address this serious issue effectively. Awareness campaigns, early detection programs, and genetic testing facilities should be prioritized to identify at-risk individuals and provide timely interventions. Collaborative efforts between the government, medical practitioners, and researchers are essential to tackle the growing breast cancer burden in the country.


Breast cancer; Hereditary breast cancer; ATRIP gene mutation; Pakistani population

Cite the Article:

Ahmed S, Ansari AI, Ansari Z. The Future of Breast Cancer in Pakistan in the Age of New Gene Mutation. Clin Case Rep Int. 2023; 7: 1601.

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