Journal Basic Info
- Impact Factor: 0.285**
- H-Index: 6
- ISSN: 2638-4558
- DOI: 10.25107/2638-4558
Major Scope
- Renal Disease
- Emergency Medicine and Critical Care
- Nuclear Medicine
- Epidemiology
- Pediatrics
- Respiratory Medicine
- Anatomy
- Traumatology
Abstract
Citation: Clin Case Rep Int. 2024;8(1):1651.DOI: 10.25107/2638-4558.1651
Infiltration of Acute Myeloid Leukemia in the Breast – A Case Report
Cristofalo MM, Ferraco Lima BL, Maesaka JY, Rios GM and Filassi JR
Department of Mastology, Division of Gynecology, Institute of Cancer of the State of São Paulo, Hospital das Clinicas, School of Medicine, University of São Paulo (HCFMUSP), Brazil
*Correspondance to: Milena Martello Cristófalo
PDF Full Text Case Report | Open Access
Abstract:
The infiltration of Acute Myeloid Leukemia (AML) in the breast is a rare condition, posing both diagnostic and therapeutic challenges. Due to the absence of specific radiological descriptions for such infiltrations, differential diagnosis with primary breast tumors becomes crucial. The authors report a case of a 19-year-old patient diagnosed with AML (FAB M2 RUNX1-RUNX1T1/t(8;21) + CKIT exon 17 mutation KIT D816V) after the term delivery of her child, with no obstetric complications. Disease recurrence occurred after the second cycle of consolidation chemotherapy, accompanied by a palpable lesion in the right breast, exhibiting progressive growth. Morphological and immunohistochemical analysis was consistent with AML infiltration of the breast parenchyma. This article contributes to the literature by presenting a rare case of AML infiltration in the breast, along with its clinical, radiological, and anatomopathological characteristics.
Keywords:
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Cite the Article:
Cristofalo MM, Ferraco Lima BL, Maesaka JY, Rios GM, Filassi JR. Infiltration of Acute Myeloid Leukemia in the Breast – A Case Report. Clin Case Rep Int. 2024; 8: 1651.