Journal Basic Info

  • Impact Factor: 0.285**
  • H-Index: 6
  • ISSN: 2638-4558
  • DOI: 10.25107/2638-4558
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Epidemiology
  •  Obstetrics and Gynecology
  •  Anesthesiology and Pain Medicine
  •  Cardiac Surgery
  •  Molecular Biology
  •  Hepatitis
  •  Pain Management
  •  Transplantation Medicine


Citation: Clin Case Rep Int. 2024;8(1):1679.DOI: 10.25107/2638-4558.1679

Safety of PEGylated Hyaluronic Acid Filler for the Treatment of Facial Skin Aging: Case Report

Kubik P and Gruszczyński W

K-LAB Badania I Rozwój, 81-312 Gdynia, Poland

*Correspondance to: Paweł Kubik 

 PDF  Full Text Case Report | Open Access


Background: The face is the area most exposed to the normal course of skin aging, both intrinsically and extrinsically. Aim: The aim of the case report was to evaluate the cellular and clinical response of a therapeutic protocol aimed at countering facial skin aging. Materials and Methods: One female patient with facial skin laxity and photodamage underwent treatment protocol of implementation of PEG-cross-linked hyaluronic acid soft tissue fillers. Results: The histological results at 0, 7, 14 and 21 days after the procedure showed an increase in the number of fibroblasts and angiogenesis, at the same time it was shown that the treatment has an immunomodulating action. Conclusion: A treatment with PEG-cross-linked hyaluronic acid leads to numerous positive cutaneous changes after histological and immunological evaluations.


HA PEGylated filler; PEG-cross-linked hyaluronic acid; Facial skin aging

Cite the Article:

Kubik P, Gruszczyński W. Safety of PEGylated Hyaluronic Acid Filler for the Treatment of Facial Skin Aging: Case Report. Clin Case Rep Int. 2024; 8: 1679.

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