Laparoscopic Trans Gastric Resection of a Large Posterior Gastric GIST Near the Gastroesophageal Junction: A Case Report

Maglio R, Del Coco F*, Fracasso M and Fracasso LA
 

Department of General Surgery, Ospedale “V. Delli Ponti”, Scorrano (LE), ASL Lecce, Italy

^*Correspondance to: Federica Del Coco 

 PDF  Full Text Case Report | Open Access

Abstract:

Background: Gastrointestinal Stromal Tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. Complete surgical resection with negative margins (R0) remains the standard of care for localized disease. However, GISTs arising near the Gastroesophageal Junction (GEJ) present a significant technical. Challenge: Conventional wedge resection may compromise gastric anatomy and function, or necessitate extended gastric resection. Case Presentation: A 53-year-old woman presented with melena and anemia due to a 9 cm × 10 cm posterior gastric wall GIST located at the lesser curvature near the GEJ. Following a lack of response to neoadjuvant imatinib therapy, she underwent laparoscopic trans gastric resection. After anterior gastrotomy, the tumor was everted and resected using a laparoscopic linear stapler, preserving uninvolved gastric tissue. The postoperative course was uneventful, and histopathological examination confirmed R0 resection of a low-risk GIST. Conclusion: Laparoscopic trans gastric resection is a safe and organ-preserving approach for large posterior gastric GISTs near the GEJ. This technique provides adequate oncologic resection while minimizing gastric deformity and preserving physiological function.

Keywords:

Laparoscopic; Submucosa; Gastrointestinal

Cite the Article:

Maglio R, Del Coco F, Fracasso M, Fracasso LA. Laparoscopic Trans Gastric Resection of a Large Posterior Gastric GIST Near the Gastroesophageal Junction: A Case Report. Clin Case Rep Int. 2026; 10: 1789..