Clin Case Rep Int | Volume 6, Issue 1 | Case Report | Open Access

Lifelong Complications of Osteogenesis Imperfecta: Case Report and Literature Review

Liviu-Iulian L*, Ungureanu R, Toma M, Angheluță C, Ioana-Marina G and Mirea LE
 

Department of Anesthesia and Intensive Care, Clinical Emergency Hospital of Bucharest, Romania

*Correspondance to: Liviu-Iulian Lovin 

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Abstract

Osteogenesis Imperfecta (OI) is a rare inherited connective tissue disorder with many phenotypic presentations, often called “brittle bone disease”. Diagnosis is straight forward in individuals with bone fragility and a positive family history or several extra skeletal manifestations (hearing loss, dark or bluish sclera). OI is classified into a number of major subtypes based on genetic, radiographic, and clinical characteristics, but more useful is the clinical classification, based upon the typical problems that manifest in infants, children, and adults with mild, moderate to severe and lethal disease. This case report describes a 53-year old female patient with an unknown genetic disorder, but with medical history of bone fragility, currently presented with spontaneous ace tabular fracture that led to the diagnosis of osteogenesis imperfect a type I. OI is associated with multiple perioperative complications, thus the patients require extensive preoperative evaluation and an individualized surgical and anesthetic management.

Keywords:

Osteogenesis imperfecta; COVID-19; Periarticular

Citation:

Liviu-Iulian L, Ungureanu R, Toma M, Angheluță C, Ioana-Marina G, Mirea LE. Lifelong Complications of Osteogenesis Imperfecta: Case Report and Literature Review. Clin Case Rep Int. 2022; 6: 1403.

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