Varicella Infection May Cause Thrombosis: A Case Report

Ozgur Dagli, Derya Ozturk Engin, Seyfi Ozyurek, Asuman Inan, Nurgul Ceran and Refik Demirtunc

Department of Infectious Diseases and Clinical Microbiology, Haydarpasa Numune Training and Research Hospital, Turkey
Department of Internal Medicine, Haydarpasa Numune Training and Research Hospital, Turkey

^*Correspondance to: Ozgur Dagli 

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Abstract:

This case was presented due to development of DVT and pulmonary embolism after VZV infection and determination of Factor V Leiden mutation and activated protein C resistance. A 19-year old male patient presented with fever at the 10th day of Varicella Zoster Virus (VZV) infection, and pruritic vesicopustular skin lesions and increased leukocyte and CRP levels. Acyclovir and ampicillin-sulbactam therapy were started. On the fourth day of hospitalization, left leg DVT and pulmonary embolism developed. Anticoagulant therapy was started. Tests revealed activated protein C resistance and Factor V Leiden mutation. The patient was discharged after the relief of symptoms with anticoagulant therapy. Thrombosis rarely develops in the course of VZV infection. It is essential to investigate the factors contributing to predisposition to thrombosis in patients with thrombosis.

Keywords:

Varicella zoster infection; Factor V leiden mutation; Thrombosis

Cite the Article:

Dagli O, Engin DO, Ozyurek S, Inan A, Ceran N, Demirtunc R. Varicella Infection May Cause Thrombosis: A Case Report. Clin Case Rep Int. 2018; 2: 1065.