Pregnancy is rarely encountered with liver cirrhosis, but carries a significant risk of complications with poor materno-fetal outcomes.
Published on 07 Nov, 2018
We report about a case of a 13-year-old boy with recurrent respiratory papillomatosis.
Published on 29 Oct, 2018
Neck mass poses treatment challenges if not properly addressed and investigated.
Published on 29 Oct, 2018
As visual classification of Fetal Heart Rate (FHR) patterns into early, late and variable decelerations was vague and complicated, correct numeric threshold setting has been started from Maeda’s FHR score in 1969 [1,2].
Published on 31 Oct, 2018
Congenital toxoplasmosis is a neglected protozoonotic disease of intercontinental distribution with incidence estimated in 1.5 cases per 1000 live births.
Published on 13 Oct, 2018
A 63-years old female presented to our clinic, as a referral for ocular examination following a diagnosis of Herpes Zoster Ophthalmicus.
Published on 12 Oct, 2018
Background: Paraganglioma of head and neck is a rare tumor and vagal schwannoma is even rarer.
Published on 11 Oct, 2018
We report a case of giant spermatic cord liposarcoma in an 80 year old patient, initially treated as an inguinal hernia due to a large left inguinoscrotal mass.
Published on 28 Sep, 2018
Nephrotic syndrome is a common presentation of lupus nephritis. In patient with Systemic Lupus Erythematosus (SLE) and the nephrotic syndrome, the two most common renal biopsy findings are diffuse proliferative lupus nephritis [World Health Organization (WHO) class IV] and membranous lupus nephritis (WHO class V).
Published on 28 Sep, 2018
A man aged 64 with localized nodular myositis which was one of the clinical features of fibrosing polymyositis is described.
Published on 28 Sep, 2018
Psoriasis is a skin ailment thought to be related to a suppressed immune system with its onset brought on about certain triggers including temperature fluctuations, infections, and stress.
Published on 22 Sep, 2018
Patients with resistant schizophrenia are commonly treated with Clozapine. They can develop epileptic seizure.
Published on 14 Sep, 2018
Clozapine remains the reference treatment in resistant schizophrenia. However, its effectiveness is obtained only in 30% to 50% of cases.
Published on 13 Sep, 2018
A 61-year old woman with multiple chronic conditions was admitted to hospital due to central vertigo, headaches, unsteady gait and frequent stumbling in the previous six months with recently appearing nausea and vomiting.
Published on 11 Sep, 2018
Major Depressive Disorder (MDD) is the most common mental health disorder in the United States as well as all over the world.
Published on 07 Sep, 2018
Symptomatic treatment for symptoms and signs of cold flu is often prescribed.
Published on 01 Sep, 2018
Mumps is generally a mild childhood disease. However, Mumps virus can infect adults as well and various complications such as orchitis, encephalitis and pancreatitis can occur.
Published on 27 Aug, 2018
The present perspective is a synthesis of all published literature on selective vertical vein patency and adjustable vertical vein ligature in the setting of rechanneling of obstructed supracardiac totally anomalous pulmonary venous connection (TAPVC) in order to decrease the episodes of perioperative pulmonary hypertensive crises, postoperative low cardiac output syndrome and mortality. Additionally, this manuscript attempts to address the guidelines for candidate selection for selective vertical vein patency in patients with obstructive supracardiac TAPVC.
Published on 07 Aug, 2018
This case was presented due to development of DVT and pulmonary embolism after VZV infection and determination of Factor V Leiden mutation and activated protein C resistance.
Published on 20 Aug, 2018
Infertility in males is big issues in Pakistan. In the current study we analyzed the level of seminal zinc concentration in various group of infertile males and to link it with sperm concentrations, inactive, active and immotile fractions of seminal constraints, with an objective to begin the role of zinc.
Published on 07 Aug, 2018
We report a highly unusual case of a patient with nephrotic syndrome due to AHL primary amyloidosis, with α heavy chain fragments in serum and urine after a recent diagnosis of renal cell carcinoma.
Published on 30 Jul, 2018
A 63-year old patient who underwent previously colectomy for colonic adenocarcinoma presented with gastric pain.
Published on 24 Jul, 2018
A 20 years old patient was hospitalized for erythema multiforme secondary to oropharyngeal herpes simplex virus type 1.
Published on 24 Jul, 2018
A 58-year-old woman with hepatitis B virus-related hepatocellular carcinoma (HCC) was treated by transarterial chemoembolization (TACE).
Published on 24 Jul, 2018
Dermoid cysts are benign lesions that rarely occur in the floor of the mouth. They can be divided in epidermoid, dermoid and teratoid cysts.
Published on 24 Jul, 2018
The topical calcineurin inhibitors have an effect on various cells of the cutaneous immune system, specifically on T-cells, by inhibiting the phosphatase calcineurin and preventing the transcription of proinflammatory cytokines.
Published on 24 Jul, 2018
Yolk sac tumor, also called endodermal sinus tumor, is a rare ovarian neoplasm, representing the second ovarian germinal neoplasm subtype after dysgerminoma, it classically occurs in adolescent and young women.
Published on 12 Jul, 2018
A 50 year old previously fit and well lady presented with septic shock.
Published on 06 Jul, 2018
Diffuse Idiopathic Skeletal Hyperostosis, also known as DISH or Forestier-Rotes-Querol disease can be an uncommon cause of Dysphagia.
Published on 14 Jun, 2018
Primary Cutaneous Gamma-Delta T-Cell Lymphoma (PCGDTCL) comprises of less than 1% of primary Cutaneous T-Cell Lymphomas (CTCL).
Published on 25 May, 2018
A 39-year-old man with no medical history presented with a 1-month history of severe wet cough and fever and 1-week history of left chest pain.
Published on 04 Apr, 2018
A 59-year old man with hepatitis C, liver cirrhosis, and multiple hepatocellular carcinoma had previously been treated with trans-catheter arterial chemoembolization.
Published on 04 Apr, 2018
Introduction: Epilepsy is a common neurological disorder prevalent among 7 out of 1,000 people in general population.
Published on 22 May, 2018
We present a case of 69-year-old woman, who was referred to our hospital with the diagnosis of Chronic Kidney Disease (CKD) stage IV with unknown etiology.
Published on 22 May, 2018
Hormonal migraine is defined as the unilateral severe headaches that occur in reproductive aged women usually 7 days premenstrual to 3 days after onset of menses.
Published on 21 May, 2018
Background: Cerebral Palsy (CP) is a permanent disorder of movement and posture, causing activity limitation and gait disturbances.
Published on 24 May, 2018
We present the case of an unusual chest finding and unique cardiac intervention for a high-risk heart failure patient.
Published on 21 May, 2018
Chylomicron Retention Disease (Anderson’s disease) is a rare autosomal recessive disorder caused by mutation of the SAR1B gene that leads to hypercholesterolemia and accumulation of lipoproteins in the enterocytes.
Published on 01 May, 2018
Benign uterine leiomyomas are the most common pelvic tumors, impairing natural delivery.
Published on 19 Apr, 2018
A 49-year-old Caucasian male was referred to the nephrology clinic in view of a rise in serum creatinine from baseline of 80 mmol/L to 125 mmol/L and intermittent macroscopic haematuria.
Published on 21 Mar, 2018
Infection and thrombosis are the two most common complications associated with the use of Central Venous Catheters (CVC).
Published on 15 Mar, 2018
Clubbing is a sign that is usually found in association chronic respiratory diseases or cyanotic cardiac conditions.
Published on 26 Feb, 2018
Background: More than 80% of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) patients suffer from migraine.
Published on 26 Feb, 2018
Ecthyma gangrenosum is a skin lesion generally associated with Pseudomonas aeruginosa, and is generally seen in immune compromised patients.
Published on 26 Feb, 2018
Primary angiitis is a rare disorder and is difficult to diagnose.
Published on 26 Feb, 2018
Children can present wheezing episodes early on life. Among pediatric population this is a very common respiratory symptom which to improve quality of can evolve into severe life-endangering episodes.
Published on 23 Feb, 2018
Primary pulmonary synovial sarcoma is rare and poses a diagnostic challenge when unusual histologic features are present and t(x; 18) is negative.
Published on 29 Jan, 2018
Tolperizol (Mydocalm) is a widely used drug as a skeletal muscle relaxant and is often additionally prescribed by family doctors in the course of lumbar discopathy.
Published on 18 Jan, 2018
Gestational Trophoblastic Disease (GTD) refers to a group of disorders including partial, complete and invasive molar pregnancy, choriocarcinoma and the less common placental site trophoblastic tumours.
Published on 18 Jan, 2018
Background & Purpose: The knee is the most common site of injury in running athletes. An often overlooked contributor to lateral knee pain is the Proximal Tibiofibular Joint (PTFJ).
Published on 19 Dec, 2017
In March 2013, a 50-year-old smoker without medical history presented with asthenia and weight loss (4 kg).
Published on 25 Nov, 2017
We present a case of a 68-year-old woman with a complicated history of multiple cancers including diffuse large B-cell lymphoma in the left femur who presented with a pathologic fracture through a radiation induced angiosarcoma of her prior treated bone.
Published on 23 Nov, 2017
This case regarding a Caucasian female patient who suffered from discoloration and rhytides on her face, neck and chest with a past history of non-melanoma skin cancer followed by Mohs micrographic surgery.
Published on 22 Nov, 2017
We present a case of intractable hiccups following a cervical epidural steroid injection (ESI).
Published on 07 Nov, 2017
A 20-year-old male presented with intermittent passage of bright red blood per rectum.
Published on 07 Nov, 2017
A 33-year-old Caucasian Italian female was admitted at the Campus Bio-Medico in Rome for a lip swelling evaluation of increased in last 4 days associated orofacial edema, yellowish vesicles, erosion over lips.
Published on 17 Oct, 2017
More than 30 years ago after the escalation of obesity in the mid 1980’s, this country continues to struggle with ways to reduce obesity and its associated co-morbidities.
Published on 17 Oct, 2017
An 18-year-old female patient presented by vomiting of 2 years duration related to meals, progressive course and associated with loss of weight.
Published on 04 Oct, 2017
This 66-year-old male developed an enterocutanous fistula following robotic assisted laparoscopic converted to open radical prostatectomy for prostate cancer.
Published on 04 Oct, 2017
Central Nervous System (CNS) metastasis cause serious clinical deterioration in patient with Non- Small Cell Lung Cancer (NSCLC).
Published on 01 Oct, 2017
Breast cancer is the most common cancer in women. Metastatic disease involvement of the stomach is usually a manifestation of advanced disease.
Published on 23 Sep, 2017
Potter syndrome (PS) is a term used to describe a typical physical appearance, which is the result of dramatically decreased amniotic fluid volume secondary to renal diseases such as bilateral renal agenesis (BRA).
Published on 22 Sep, 2017
Objective: Velopharyngeal insufficiency is usually defined as failure of the velopharyngeal sphincter (mainly: velum, lateral and posterior pharyngeal walls) to separate the oropharynx from the nasopharyngeal space during speech and deglutition resulting in swallowing and speech difficulties with adverse effects on communication skills and the psychological status of the patient.
Published on 10 Sep, 2017
An extremely preterm infant developed severe unilateral pulmonary interstitial emphysema of the left lung.
Published on 07 Sep, 2017
Respiratory distress in newborns within the first hours after birth includes airway obstruction etiologies.
Published on 31 Aug, 2017
Background: With only about a hundred published cases at this time, sinonasal teratocarcinosarcoma is a rare disease managed definitively with surgery and adjuvant radiotherapy with concurrent chemotherapy.
Published on 28 Aug, 2017
A 45-year-old white female presented with a four-week history of worsening abdominal pain, sore throat, fever, and night sweats.
Published on 17 Aug, 2017
We report a case of a 49-year-old man who presented acutely with abdominal pain due to caecal MANEC with liver metastasis.
Published on 17 Aug, 2017
Aim: We have reviewed our ruptured and non-ruptured infected Abdominal Aortic Aneurysms (AAA) to study the clinical presentation, management and eventual outcome of patients managed with endovascular repair.
Published on 10 Aug, 2017
Cervical cancer encompasses several histologic types, of which Squamous Cell Carcinoma (SCC) is the most common (70 percent).
Published on 25 Jul, 2017
A 68-year-old man was analyzed for dysphagia and weight loss. His medical history revealed a stadium III-IV non-Hodgkin lymphoma for which was treated with radiation therapy 40 years ago.
Published on 13 Jul, 2017
We present a case of Yersinia enterocolitica bacteremia and sepsis with multiple liver abscesses mimicking metastatic liver disease.
Published on 13 Jul, 2017
A case is presented of inadequate hospital care in a pregnant woman with fetal growth restriction (FGR) and oligohydramnios, which resulted in intrauterine fetal death with the cause of death concealed by the obstetrician.
Published on 10 Jul, 2017
Introduction: Placental mesenchymal dysplasia (PMD) is a rare lesion, characterized by atypical placental development with placentomegaly, hydropic cystic stem villi formation and anomalous villous stroma and vessels.
Published on 10 Jul, 2017
Ewing sarcoma family of tumors is highly aggressive, with common local recurrence and distant metastases.
Published on 10 Jul, 2017
We present the case of a 28-year-old woman in her first pregnancy. First trimester ultrasound screening for aneuploidies (NT, β-hCG and PAPP-A) was negative.
Published on 08 Jul, 2017
Hereditary thrombophilia is viewed as a possible factor for repeated pregnancy loss (RPL), resulting in the onset of thrombotic events at the placenta that lead to adverse pregnancy outcome.
Published on 28 Jun, 2017
Elemental diet (ED) is an efficacious treatment for patients with Crohn’s disease (CD).
Published on 26 May, 2017
There has been burgeoning of knowledge brought about by the introduction of molecular and immuno markers in the evolution of various types of lung cancer and management.
Published on 31 May, 2017
Malignant melanoma is rare in children younger than 15 years, accounting for less than 1% of pediatric malignancies.
Published on 18 May, 2017
Orbital metastases from malignant tumors are relatively uncommon. In 25% of cases it is the first manifestation of an undiagnosed cancer.
Published on 11 May, 2017
The term achondroplasia means syndrome whose main characteristics are low growth, dwarfism, due to short limbs.
Published on 12 Apr, 2017
Renowned Editors
MIT, John Hopkins University, Stanford University, University of Michigan...300+
Rapid Peer Review
We assure 20 days rapid peer review process
Open Access
Open Access is the free, immediate, online availability of novel research
High Visibility
Published articles are easy to find on google, google scholar and other databases