Case Study

Peripartum Decompensation Uncovering Underlying Asymptomatic Cirrhosis and Portal Hypertension: An Unusual Case Report

Pregnancy is rarely encountered with liver cirrhosis, but carries a significant risk of complications with poor materno-fetal outcomes.

Published on 07 Nov, 2018


Case Report

Narrow Band Imaging of Recurrent Respiratory Papillomatosis

We report about a case of a 13-year-old boy with recurrent respiratory papillomatosis.

Published on 29 Oct, 2018


Case Report

Dilemmas in Diagnosing Neck Mass: Branchial Cyst versus Thyroid Tumor

Neck mass poses treatment challenges if not properly addressed and investigated.

Published on 29 Oct, 2018


Case Study

Fetal Monitoring Changed to Simple Numeric Decision Discarding Fetal Heart Rate Pattern Classification

As visual classification of Fetal Heart Rate (FHR) patterns into early, late and variable decelerations was vague and complicated, correct numeric threshold setting has been started from Maeda’s FHR score in 1969 [1,2].

Published on 31 Oct, 2018


Mini Review

Major Serological Screening Methodologies to Anti- T. Gondii Antibodies Detection in Pregnancy: Mini Literature View

Congenital toxoplasmosis is a neglected protozoonotic disease of intercontinental distribution with incidence estimated in 1.5 cases per 1000 live births.

Published on 13 Oct, 2018


Clinical Image

Herpes Zoster Ophthalmicus-Induced Oculomotor Nerve Palsy

A 63-years old female presented to our clinic, as a referral for ocular examination following a diagnosis of Herpes Zoster Ophthalmicus.

Published on 12 Oct, 2018


Case Report

Surgical Resection of Vagal Schwannoma in a Young Female

Background: Paraganglioma of head and neck is a rare tumor and vagal schwannoma is even rarer.

Published on 11 Oct, 2018


Case Report

Giant Spermatic Cord Liposarcoma in Older Patient: Case Report

We report a case of giant spermatic cord liposarcoma in an 80 year old patient, initially treated as an inguinal hernia due to a large left inguinoscrotal mass.

Published on 28 Sep, 2018


Case Report

Focal Segmental Glomerulosclerosis in Systemic Lupus Erythematosus

Nephrotic syndrome is a common presentation of lupus nephritis. In patient with Systemic Lupus Erythematosus (SLE) and the nephrotic syndrome, the two most common renal biopsy findings are diffuse proliferative lupus nephritis [World Health Organization (WHO) class IV] and membranous lupus nephritis (WHO class V).

Published on 28 Sep, 2018


Case Report

Subacute Fibrosing Nodular Polymyositis: Nodular Variant of Polymyositis with Pronounced Contractures of “Woody” Firm Muscles and Painless Intramuscular Nodules: Report of a Case

A man aged 64 with localized nodular myositis which was one of the clinical features of fibrosing polymyositis is described.

Published on 28 Sep, 2018


Case Report

Psoriasis and Its Correlation with Depression and Body Image

Psoriasis is a skin ailment thought to be related to a suppressed immune system with its onset brought on about certain triggers including temperature fluctuations, infections, and stress.

Published on 22 Sep, 2018


Short Communication

Epileptic Seizures and Clozapine Titration

Patients with resistant schizophrenia are commonly treated with Clozapine. They can develop epileptic seizure.

Published on 14 Sep, 2018


Clinical Description

The Aripiprazole-Clozapine Association in Treatment Ultra Resistant Schizophrenia

Clozapine remains the reference treatment in resistant schizophrenia. However, its effectiveness is obtained only in 30% to 50% of cases.

Published on 13 Sep, 2018


Short Communication

Cystic Cerebellar Tumor

A 61-year old woman with multiple chronic conditions was admitted to hospital due to central vertigo, headaches, unsteady gait and frequent stumbling in the previous six months with recently appearing nausea and vomiting.

Published on 11 Sep, 2018


Case Report

Major Depressive Disorder and the “Leaky Gut” Post Cholecystectomy

Major Depressive Disorder (MDD) is the most common mental health disorder in the United States as well as all over the world.

Published on 07 Sep, 2018


Case Study

An Important Side Effect of Pseudoefedrin used in Cold Flu Treatment: Fast Ventricular Responsive Atrial Fibrillation

Symptomatic treatment for symptoms and signs of cold flu is often prescribed.

Published on 01 Sep, 2018


Case Report

Acute Pancreatitis Caused by Mumps Infection in an Adult

Mumps is generally a mild childhood disease. However, Mumps virus can infect adults as well and various complications such as orchitis, encephalitis and pancreatitis can occur.

Published on 27 Aug, 2018


Short Communication

The Vertical Vein in Patients with Obstructive Supracardiac Totally Anomalous Pulmonary Venous Connection: we can ligate it but should we ligate it?

The present perspective is a synthesis of all published literature on selective vertical vein patency and adjustable vertical vein ligature in the setting of rechanneling of obstructed supracardiac totally anomalous pulmonary venous connection (TAPVC) in order to decrease the episodes of perioperative pulmonary hypertensive crises, postoperative low cardiac output syndrome and mortality. Additionally, this manuscript attempts to address the guidelines for candidate selection for selective vertical vein patency in patients with obstructive supracardiac TAPVC.

Published on 07 Aug, 2018


Case Report

Varicella Infection May Cause Thrombosis: A Case Report

This case was presented due to development of DVT and pulmonary embolism after VZV infection and determination of Factor V Leiden mutation and activated protein C resistance.

Published on 20 Aug, 2018


Research Article

Seminal Plasma Zinc Concentration in Infertile Males in Different Classes in Islamabad, Pakistan

Infertility in males is big issues in Pakistan. In the current study we analyzed the level of seminal zinc concentration in various group of infertile males and to link it with sperm concentrations, inactive, active and immotile fractions of seminal constraints, with an objective to begin the role of zinc.

Published on 07 Aug, 2018


Case Report

A Case of Nephrotic Syndrome due to AHL Amyloidosis in a Patient with Renal Cell Carcinoma

We report a highly unusual case of a patient with nephrotic syndrome due to AHL primary amyloidosis, with α heavy chain fragments in serum and urine after a recent diagnosis of renal cell carcinoma.

Published on 30 Jul, 2018


Clinical Image

A Strange Benign Lesion of the Esophagus: Benign Bizarre Stromal Cell Polyp

A 63-year old patient who underwent previously colectomy for colonic adenocarcinoma presented with gastric pain.

Published on 24 Jul, 2018


Clinical Image

Oesophageal Localisation of Erythema Multiforme due to Herpes Simplex Virus

A 20 years old patient was hospitalized for erythema multiforme secondary to oropharyngeal herpes simplex virus type 1.

Published on 24 Jul, 2018


Clinical Image

Pulmonary Lipiodol Embolism Induced by Transarterial Chemoembolization for Hepatocellular Carcinoma

A 58-year-old woman with hepatitis B virus-related hepatocellular carcinoma (HCC) was treated by transarterial chemoembolization (TACE).

Published on 24 Jul, 2018


Case Report

Epidermoid Cyst of the Floor of the Mouth

Dermoid cysts are benign lesions that rarely occur in the floor of the mouth. They can be divided in epidermoid, dermoid and teratoid cysts.

Published on 24 Jul, 2018


Case Report

Tacrolimus Induced Photodistributed Lichenoid Eruption

The topical calcineurin inhibitors have an effect on various cells of the cutaneous immune system, specifically on T-cells, by inhibiting the phosphatase calcineurin and preventing the transcription of proinflammatory cytokines.

Published on 24 Jul, 2018


Case Report

Ovarian Yolk Sac Tumor: A Case Report and Literature Review

Yolk sac tumor, also called endodermal sinus tumor, is a rare ovarian neoplasm, representing the second ovarian germinal neoplasm subtype after dysgerminoma, it classically occurs in adolescent and young women.

Published on 12 Jul, 2018


Case Blog

Unique Case of Haemophilus Influenzae Purulent Pericarditis Secondary to Infected Mirena Coil

A 50 year old previously fit and well lady presented with septic shock.

Published on 06 Jul, 2018


Case Report

Dish: An Uncommon Cause of Dysphagia in the Elderly

Diffuse Idiopathic Skeletal Hyperostosis, also known as DISH or Forestier-Rotes-Querol disease can be an uncommon cause of Dysphagia.

Published on 14 Jun, 2018


Case Report

Cytophagic Histiocytic Panniculitis Masking as Primary Cutaneous T-Cell Lymphoma: A Spectrum of Disease

Primary Cutaneous Gamma-Delta T-Cell Lymphoma (PCGDTCL) comprises of less than 1% of primary Cutaneous T-Cell Lymphomas (CTCL).

Published on 25 May, 2018


Clinical Image

Pulmonary Tuberculosis

A 39-year-old man with no medical history presented with a 1-month history of severe wet cough and fever and 1-week history of left chest pain.

Published on 04 Apr, 2018


Clinical Image

Re-Expansion Pulmonary Edema after Therapeutic Thoracentesis

A 59-year old man with hepatitis C, liver cirrhosis, and multiple hepatocellular carcinoma had previously been treated with trans-catheter arterial chemoembolization.

Published on 04 Apr, 2018


Case Report

Misdiagnosing Epilepsy: A Case Report on Stokes - Adams Syndrome

Introduction: Epilepsy is a common neurological disorder prevalent among 7 out of 1,000 people in general population.

Published on 22 May, 2018


Case Report

A Little Review of LECT2-Associated Renal Amyloidosis (ALECT2): Is not a Rare Disease

We present a case of 69-year-old woman, who was referred to our hospital with the diagnosis of Chronic Kidney Disease (CKD) stage IV with unknown etiology.

Published on 22 May, 2018


Case Report

Menstrual Migraine and Treatment Options: Review Hormonal Therapy in the Prevention of Menstrual Migraine

Hormonal migraine is defined as the unilateral severe headaches that occur in reproductive aged women usually 7 days premenstrual to 3 days after onset of menses.

Published on 21 May, 2018


Case Report

Gait Analysis Using Wearable Sensor Inertial in a Child with CP after Orthopedic Surgery: Case Report

Background: Cerebral Palsy (CP) is a permanent disorder of movement and posture, causing activity limitation and gait disturbances.

Published on 24 May, 2018


Case Report

Cardiac Pseudo-aneurysm with Resection and LVAD Placement

We present the case of an unusual chest finding and unique cardiac intervention for a high-risk heart failure patient.

Published on 21 May, 2018


Case Report

Chylomicron Retention Disease: An Infant Presenting with Vomiting and Failure to Thrive without Diarrhea

Chylomicron Retention Disease (Anderson’s disease) is a rare autosomal recessive disorder caused by mutation of the SAR1B gene that leads to hypercholesterolemia and accumulation of lipoproteins in the enterocytes.

Published on 01 May, 2018


Case Report

Anesthetic Management for a Cesarean Delivery in a Pregnancy Complicated by Uterus Polymyomatosus: A Case Report

Benign uterine leiomyomas are the most common pelvic tumors, impairing natural delivery.

Published on 19 Apr, 2018


Clinical Image

Renal Papillary Necrosis in a Patient with Haemophilia

A 49-year-old Caucasian male was referred to the nephrology clinic in view of a rise in serum creatinine from baseline of 80 mmol/L to 125 mmol/L and intermittent macroscopic haematuria.

Published on 21 Mar, 2018


Case Report

Sepsis and Thrombosis with the Use of Central Venous Catheters during Hemodialysis

Infection and thrombosis are the two most common complications associated with the use of Central Venous Catheters (CVC).

Published on 15 Mar, 2018


Case Report

An Unusual Cause of Clubbing; the Esophageal Carcinoma

Clubbing is a sign that is usually found in association chronic respiratory diseases or cyanotic cardiac conditions.

Published on 26 Feb, 2018


Research Article

The Efficacy and Tolerability of Topiramate in Migraine Prophylaxis in CFS/ME Patients

Background: More than 80% of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) patients suffer from migraine.

Published on 26 Feb, 2018


Clinical Image

Typical Clinical Image of Ecthyma Gangrenosum

Ecthyma gangrenosum is a skin lesion generally associated with Pseudomonas aeruginosa, and is generally seen in immune compromised patients.

Published on 26 Feb, 2018


Case Report

Primary Angiitis of Central Nervous System

Primary angiitis is a rare disorder and is difficult to diagnose.

Published on 26 Feb, 2018


Case Report

Wheezing Disorders in Childhood

Children can present wheezing episodes early on life. Among pediatric population this is a very common respiratory symptom which to improve quality of can evolve into severe life-endangering episodes.

Published on 23 Feb, 2018


Case Report

Primary Pulmonary Synovial Sarcoma: Case Report with Unusual Histology and Diagnostic Pearls

Primary pulmonary synovial sarcoma is rare and poses a diagnostic challenge when unusual histologic features are present and t(x; 18) is negative.

Published on 29 Jan, 2018


Case Report

Drug Generalized Hypersensitivity Reactions to Tolperisone (Mydocalm)

Tolperizol (Mydocalm) is a widely used drug as a skeletal muscle relaxant and is often additionally prescribed by family doctors in the course of lumbar discopathy.

Published on 18 Jan, 2018


Case Report

Gestational Trophoblastic Neoplasia Arising on Scar Pregnancy: A Case Report

Gestational Trophoblastic Disease (GTD) refers to a group of disorders including partial, complete and invasive molar pregnancy, choriocarcinoma and the less common placental site trophoblastic tumours.

Published on 18 Jan, 2018


Case Report

Effectiveness of Physical Therapy Intervention to the Proximal Tibiofibular Joint for a Marathon Runner with Lateral Knee Pain

Background & Purpose: The knee is the most common site of injury in running athletes. An often overlooked contributor to lateral knee pain is the Proximal Tibiofibular Joint (PTFJ).

Published on 19 Dec, 2017


Case Blog

Pulmonary Nocardiosis Mimicking Lung Malignancy

In March 2013, a 50-year-old smoker without medical history presented with asthenia and weight loss (4 kg).

Published on 25 Nov, 2017


Case Report

Secondary Angiosarcoma of the Femur after Radiation Therapy for a Primary B-Cell Lymphoma: A Case Report

We present a case of a 68-year-old woman with a complicated history of multiple cancers including diffuse large B-cell lymphoma in the left femur who presented with a pathologic fracture through a radiation induced angiosarcoma of her prior treated bone.

Published on 23 Nov, 2017


Case Report

A Keratoacanthoma Occurring Post Non-ablative Resurfacing

This case regarding a Caucasian female patient who suffered from discoloration and rhytides on her face, neck and chest with a past history of non-melanoma skin cancer followed by Mohs micrographic surgery.

Published on 22 Nov, 2017


Case Report

Intractable Hiccups Resulting from a Cervical Epidural Steroid Injection

We present a case of intractable hiccups following a cervical epidural steroid injection (ESI).

Published on 07 Nov, 2017


Clinical Image

Solitary Hamartomatous Polyp of the Large Colon

A 20-year-old male presented with intermittent passage of bright red blood per rectum.

Published on 07 Nov, 2017


Case Report

Idiopathic Melkersson-Rosenthal Syndrome: A Case Report

A 33-year-old Caucasian Italian female was admitted at the Campus Bio-Medico in Rome for a lip swelling evaluation of increased in last 4 days associated orofacial edema, yellowish vesicles, erosion over lips.

Published on 17 Oct, 2017


Commentary

Redefining the Course of Obesity Prevention

More than 30 years ago after the escalation of obesity in the mid 1980’s, this country continues to struggle with ways to reduce obesity and its associated co-morbidities.

Published on 17 Oct, 2017


Case Blog

A Stomach in the Stomach: A Huge Trichobezoars in Young Female

An 18-year-old female patient presented by vomiting of 2 years duration related to meals, progressive course and associated with loss of weight.

Published on 04 Oct, 2017


Case Report

Case Report: Enterocutaneous Fistula Following Radical Prostatectomy

This 66-year-old male developed an enterocutanous fistula following robotic assisted laparoscopic converted to open radical prostatectomy for prostate cancer.

Published on 04 Oct, 2017


Case Report

Leptomeningeal Metastasis in Non-Small Cell Lung Cancer: A Report of Two Cases and Short Rewiev of Literature

Central Nervous System (CNS) metastasis cause serious clinical deterioration in patient with Non- Small Cell Lung Cancer (NSCLC).

Published on 01 Oct, 2017


Case Report

Metastatic Breast Cancer First Presenting as a Primary Gastric Carcinoma

Breast cancer is the most common cancer in women. Metastatic disease involvement of the stomach is usually a manifestation of advanced disease.

Published on 23 Sep, 2017


Editorial

Potter Syndrome: A Case Study

Potter syndrome (PS) is a term used to describe a typical physical appearance, which is the result of dramatically decreased amniotic fluid volume secondary to renal diseases such as bilateral renal agenesis (BRA).

Published on 22 Sep, 2017


Clinical Images

Velopharyngeal Insufficiency after Dental Trauma: A Case Report

Objective: Velopharyngeal insufficiency is usually defined as failure of the velopharyngeal sphincter (mainly: velum, lateral and posterior pharyngeal walls) to separate the oropharynx from the nasopharyngeal space during speech and deglutition resulting in swallowing and speech difficulties with adverse effects on communication skills and the psychological status of the patient.

Published on 10 Sep, 2017


Case Report

Treatment of Severe Unilateral Pulmonary Interstitial Emphysema in a Preterm Infant

An extremely preterm infant developed severe unilateral pulmonary interstitial emphysema of the left lung.

Published on 07 Sep, 2017


Case Report

Maternal Blood Aspiration Syndrome

Respiratory distress in newborns within the first hours after birth includes airway obstruction etiologies.

Published on 31 Aug, 2017


Case Report

Recurrent Sinonasal Teratocarcinosarcoma Treated with Surgery and Post-operative Intensity Modulated Radiotherapy (IMRT): A Case Report

Background: With only about a hundred published cases at this time, sinonasal teratocarcinosarcoma is a rare disease managed definitively with surgery and adjuvant radiotherapy with concurrent chemotherapy.

Published on 28 Aug, 2017


Case Report

Acute Infectious Mononucleosis Complicated by Splenic Infarcts

A 45-year-old white female presented with a four-week history of worsening abdominal pain, sore throat, fever, and night sweats.

Published on 17 Aug, 2017


Case Report

Management Challenges of Colorectal Mixed Adeno-Neuroendocrine Carcinoma (MANEC): Case Report and Literature Review

We report a case of a 49-year-old man who presented acutely with abdominal pain due to caecal MANEC with liver metastasis.

Published on 17 Aug, 2017


Case Report

Outcomes for Endovascular Repair of Infected Abdominal Aortic Aneurysms

Aim: We have reviewed our ruptured and non-ruptured infected Abdominal Aortic Aneurysms (AAA) to study the clinical presentation, management and eventual outcome of patients managed with endovascular repair.

Published on 10 Aug, 2017


Editorial

Villoglandular Papillary Adenocarcinoma of the Cervix

Cervical cancer encompasses several histologic types, of which Squamous Cell Carcinoma (SCC) is the most common (70 percent).

Published on 25 Jul, 2017


Clinical Image

A Patient with Fever after Neoadjuvant Chemoradiotherapy for Esophageal Cancer

A 68-year-old man was analyzed for dysphagia and weight loss. His medical history revealed a stadium III-IV non-Hodgkin lymphoma for which was treated with radiation therapy 40 years ago.

Published on 13 Jul, 2017


Case Report

Yersinia enterocolitica Bacteremia and Multiple Liver Abscesses Disclose a Colonic Tubular Adenoma

We present a case of Yersinia enterocolitica bacteremia and sepsis with multiple liver abscesses mimicking metastatic liver disease.

Published on 13 Jul, 2017


Case Report

Masking Medical Error in Obstetrics – Clinical Forensic and Bioethical Considerations

A case is presented of inadequate hospital care in a pregnant woman with fetal growth restriction (FGR) and oligohydramnios, which resulted in intrauterine fetal death with the cause of death concealed by the obstetrician.

Published on 10 Jul, 2017


Case Report

Placental Mesenchymal Dysplasia with Fetal Mosaicism – A Case Report

Introduction: Placental mesenchymal dysplasia (PMD) is a rare lesion, characterized by atypical placental development with placentomegaly, hydropic cystic stem villi formation and anomalous villous stroma and vessels.

Published on 10 Jul, 2017


Case Report

An Aggressive Small Round Blue Malignancy in the Intensive Care Unit

Ewing sarcoma family of tumors is highly aggressive, with common local recurrence and distant metastases.

Published on 10 Jul, 2017


Clinical Image

Clinical Case: A 28-Year-Old G1P0 with Mild Ventriculomegaly

We present the case of a 28-year-old woman in her first pregnancy. First trimester ultrasound screening for aneuploidies (NT, β-hCG and PAPP-A) was negative.

Published on 08 Jul, 2017


Case Report

Intervention of Low-Molecular-Weight Heparin in M2/ ANXA5 Haplotype Carriers: A Case Report in Pregnancy

Hereditary thrombophilia is viewed as a possible factor for repeated pregnancy loss (RPL), resulting in the onset of thrombotic events at the placenta that lead to adverse pregnancy outcome.

Published on 28 Jun, 2017


Case Report

Selenium Deficiency during Long-Term Management of Crohn’s Disease with Full Elemental Diet: A Case Report

Elemental diet (ED) is an efficacious treatment for patients with Crohn’s disease (CD).

Published on 26 May, 2017


Editorial

Lung Cancer Diagnostics and Prognostics - Tissue Is an Issue

There has been burgeoning of knowledge brought about by the introduction of molecular and immuno markers in the evolution of various types of lung cancer and management.

Published on 31 May, 2017


Case Report

Transplacental Transmission of Melanotic Tumor in an 8-Month Old Female Infant: A Case Report

Malignant melanoma is rare in children younger than 15 years, accounting for less than 1% of pediatric malignancies.

Published on 18 May, 2017


Case Report

Orbital Metastasis as the Initial Manifestation of Lung Carcinoma: Case Report and Usefulness of 18F-FDG PET/ CT

Orbital metastases from malignant tumors are relatively uncommon. In 25% of cases it is the first manifestation of an undiagnosed cancer.

Published on 11 May, 2017


Editorial

Orofacial Aspects of Young Patients with Achondroplasia

The term achondroplasia means syndrome whose main characteristics are low growth, dwarfism, due to short limbs.

Published on 12 Apr, 2017





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